Susceptibility to gut leakiness: a possible mechanism for endotoxaemia in non-alcoholic steatohepatitis

INTRODUCTION: One of the proposed second hit mechanisms in the pathophysiology of non-alcoholic steatohepatitis (NASH) is hepatic oxidative stress triggered by elevated levels of endotoxin. We investigated one possible mechanism for the endotoxaemia – disruption of intestinal barrier integrity. METH...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Farhadi, Ashkan, Gundlapalli, Sushama, Shaikh, Maliha, Frantzides, Constantine, Harrell, Laura, Kwasny, Mary M., Keshavarzian, Ali
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303249/
https://ncbi.nlm.nih.gov/pubmed/18397235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1478-3231.2008.01723.x
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