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CYP2E1 potentiates binge alcohol-induced gut leakiness, steatohepatitis and apoptosis

Ethanol-inducible cytochrome P450 2E1 (CYP2E1) contributes to increased oxidative stress and steatosis in chronic alcohol-exposure models. However, its role in binge ethanol-induced gut leakiness and hepatic injury is unclear. This study was aimed to investigate the role of CYP2E1 in binge alcohol-i...

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Autors principals: Abdelmegeed, Mohamed A., Banerjee, Atrayee, Jang, Sehwan, Yoo, Seong-Ho, Yun, Jun-Won, Gonzalez, Frank J., Keshavarzian, Ali, Song, Byoung-Joon
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859835/
https://ncbi.nlm.nih.gov/pubmed/24064383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.09.009
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