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Critical role of cytochrome P450 2E1 (CYP2E1) in the development of high fat-induced nonalcoholic steatohepatitis

BACKGROUND & AIMS: Ethanol-inducible cytochrome P450 2E1 (CYP2E1) activity contributes to oxidative stress. However, CYP2E1 may have an important role in the pathogenesis of high-fat mediated nonalcoholic steatohepatitis (NASH). Thus, the role of CYP2E1 in high-fat mediated NASH development was...

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Detalhes bibliográficos
Main Authors: Abdelmegeed, Mohamed A., Banerjee, Atrayee, Yoo, Seong-Ho, Jang, Sehwan, Gonzalez, Frank J., Song, Byoung-Joon
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3445664/
https://ncbi.nlm.nih.gov/pubmed/22668639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2012.05.019
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