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Apoptosis of enterocytes and nitration of junctional complex proteins promote alcohol-induced gut leakiness and liver injury

BACKGROUND & AIMS: Binge alcohol causes gut leakiness, contributing to increased endotoxemia and inflammatory liver injury, although the molecular mechanisms are still elusive. This study was aimed at investigating the roles of apoptosis of enterocytes and nitration followed by degradation of in...

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Vydáno v:J Hepatol
Hlavní autoři: Cho, Young-Eun, Yu, Li-Rong, Abdelmegeed, Mohamed A., Yoo, Seong-Ho, Song, Byoung-Joon
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008177/
https://ncbi.nlm.nih.gov/pubmed/29458168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2018.02.005
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