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Evidence that chronic alcohol exposure promotes intestinal oxidative stress, intestinal hyperpermeability and endotoxemia prior to development of alcoholic steatohepatitis in rats
BACKGROUND/AIMS: Not all alcoholics develop liver disease (ALD). Thus, excessive ethanol consumption is necessary, but not sufficient, to induce alcoholic steatohepatitis (ASH) & ALD. Since endotoxemia is present in patients with ALD, it has been proposed that gut-derived, circulating endotoxin...
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| Główni autorzy: | , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2008
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2680133/ https://ncbi.nlm.nih.gov/pubmed/19155080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2008.10.028 |
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