In vivo anti-LAP mAb enhances IL-17/IFN-γ responses and abrogates anti-CD3-induced oral tolerance

Regulatory T cells (Tregs) play a critical role in the maintenance of immunological tolerance. The best-characterized Tregs are those expressing the transcription factor Foxp3 and in vivo modulation of Foxp3 Tregs has been employed to study their role in immune homeostasis. Latency-associated peptid...

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Bibliografiska uppgifter
I publikationen:Int Immunol
Huvudupphovsmän: da Cunha, Andre P., Wu, Henry Y., Rezende, Rafael M., Vandeventer, Tyler, Weiner, Howard L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Oxford University Press 2015
Ämnen:
Featured Article of the Month
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4303004/
https://ncbi.nlm.nih.gov/pubmed/25194146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxu083
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