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The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors

Omalizumab is an anti-IgE monoclonal antibody (mAb) approved for the treatment of severe asthma and chronic spontaneous urticaria. Use of omalizumab is associated with reported side effects ranging from local skin inflammation at the injection site to systemic anaphylaxis. To date, the mechanisms th...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Balbino, Bianca, Herviou, Pauline, Godon, Ophélie, Stackowicz, Julien, Goff, Odile Richard-Le, Iannascoli, Bruno, Sterlin, Delphine, Brûlé, Sébastien, Millot, Gael A., Harris, Faith M., Voronina, Vera A., Nadeau, Kari C., Macdonald, Lynn E., Murphy, Andrew J., Bruhns, Pierre, Reber, Laurent L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7269578/
https://ncbi.nlm.nih.gov/pubmed/31770111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129697
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