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The anti-IgE mAb omalizumab induces adverse reactions by engaging Fcγ receptors
Omalizumab is an anti-IgE monoclonal antibody (mAb) approved for the treatment of severe asthma and chronic spontaneous urticaria. Use of omalizumab is associated with reported side effects ranging from local skin inflammation at the injection site to systemic anaphylaxis. To date, the mechanisms th...
Guardat en:
| Publicat a: | J Clin Invest |
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| Autors principals: | , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Clinical Investigation
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7269578/ https://ncbi.nlm.nih.gov/pubmed/31770111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI129697 |
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