The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development

Low density lipoprotein receptor-related protein 1 (LRP1) is indispensable for embryonic development. Comparing different genetically engineered mouse models, we found that expression of Lrp1 is essential in the embryo proper. Loss of LRP1 leads to lethal vascular defects with lack of proper investm...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Development
Asıl Yazarlar: Nakajima, Chikako, Haffner, Philipp, Goerke, Sebastian M., Zurhove, Kai, Adelmann, Giselind, Frotscher, Michael, Herz, Joachim, Bock, Hans H., May, Petra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Company of Biologists 2014
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302929/
https://ncbi.nlm.nih.gov/pubmed/25377550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.109124
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