The lipoprotein receptor LRP1 modulates sphingosine-1-phosphate signaling and is essential for vascular development

Low density lipoprotein receptor-related protein 1 (LRP1) is indispensable for embryonic development. Comparing different genetically engineered mouse models, we found that expression of Lrp1 is essential in the embryo proper. Loss of LRP1 leads to lethal vascular defects with lack of proper investm...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Development
Päätekijät: Nakajima, Chikako, Haffner, Philipp, Goerke, Sebastian M., Zurhove, Kai, Adelmann, Giselind, Frotscher, Michael, Herz, Joachim, Bock, Hans H., May, Petra
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2014
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302929/
https://ncbi.nlm.nih.gov/pubmed/25377550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.109124
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