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γ-Secretase Mediates Self-Limitation of the Inflammatory Response by Processing LRP1

Inflammation is a potentially self-destructive process that needs tight control. We have identified a novel nuclear signaling mechanism through which the low-density lipoprotein receptor-related protein 1 (LRP1) limits transcription of lipopolysaccharide (LPS)-inducible inflammatory genes in vitro a...

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Autors principals: Zurhove, Kai, Nakajima, Chikako, Herz, Joachim, Bock, Hans H., May, Petra
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694618/
https://ncbi.nlm.nih.gov/pubmed/19036715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1164263
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