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γ-Secretase Mediates Self-Limitation of the Inflammatory Response by Processing LRP1
Inflammation is a potentially self-destructive process that needs tight control. We have identified a novel nuclear signaling mechanism through which the low-density lipoprotein receptor-related protein 1 (LRP1) limits transcription of lipopolysaccharide (LPS)-inducible inflammatory genes in vitro a...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694618/ https://ncbi.nlm.nih.gov/pubmed/19036715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.1164263 |
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