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The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap

The corpus callosum connects cerebral hemispheres and is the largest axon tract in the mammalian brain. Callosal malformations are among the most common congenital brain anomalies and are associated with a wide range of neuropsychological deficits. Crossing of the midline by callosal axons relies on...

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Publicat a:Development
Autors principals: Lavado, Alfonso, Ware, Michelle, Paré, Joshua, Cao, Xinwei
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302891/
https://ncbi.nlm.nih.gov/pubmed/25336744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.111260
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