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Withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling

The NF-κB family of transcription factors regulates numerous cellular processes, including cell proliferation and survival responses. The constitutive activation of NF-κB has also emerged as an important oncogenic driver in many malignancies, such as activated B-cell like diffuse large B cell lympho...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Jackson, Shawn S., Oberley, Christopher, Hooper, Christopher P., Grindle, Kreg, Wuerzberger-Davis, Shelly, Wolff, Jared, McCool, Kevin, Rui, Lixin, Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4302062/
https://ncbi.nlm.nih.gov/pubmed/25304104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2014.09.034
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