IPO3-mediated Nonclassical Nuclear Import of NF-κB Essential Modulator (NEMO) Drives DNA Damage-dependent NF-κB Activation

Activation of IκB kinase (IKK) and NF-κB by genotoxic stresses modulates apoptotic responses and production of inflammatory mediators, thereby contributing to therapy resistance and premature aging. We previously reported that genotoxic agents induce nuclear localization of NF-κB essential modulator...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Hwang, Byounghoon, McCool, Kevin, Wan, Jun, Wuerzberger-Davis, Shelly M., Young, Edmond W. K., Choi, Eun Young, Cingolani, Gino, Weaver, Beth A., Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505044/
https://ncbi.nlm.nih.gov/pubmed/26060253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.645960
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados