Covalent Modification of the NF-κB Essential Modulator (NEMO) by a Chemical Compound Can Regulate Its Ubiquitin Binding Properties in Vitro

Post-translational modification by ubiquitin plays important roles in multiple physiological and pathological processes. Ubiquitin-binding proteins play a critical role in recognizing and relaying polyubiquitin-based signaling. NEMO (NF-κB Essential Modulator) is a central player in canonical NF-κB...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Hooper, Christopher, Jackson, Shawn S., Coughlin, Emma E., Coon, Joshua J., Miyamoto, Shigeki
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246077/
https://ncbi.nlm.nih.gov/pubmed/25296760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582478
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