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Caveolin-1 mediated uptake via langerin restricts HIV-1 infection in human Langerhans cells
BACKGROUND: Human Langerhans cells (LCs) reside in foreskin and vaginal mucosa and are the first immune cells to interact with HIV-1 during sexual transmission. LCs capture HIV-1 through the C-type lectin receptor langerin, which routes the virus into Birbeck granules (BGs), thereby preventing HIV-1...
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| Опубликовано в: : | Retrovirology |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301922/ https://ncbi.nlm.nih.gov/pubmed/25551286 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-014-0123-7 |
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