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Effects of hypoxia on anabolic and catabolic gene expression and DNA methylation in OA chondrocytes
BACKGROUND: Cartilage is an avascular and aneural tissue. Chondrocytes thrive in this restricted environment of low oxygen tension and poor nutrient availability which has led to suggestions that hypoxia may be a protective mechanism against the development of osteoarthritis (OA). There is also a gr...
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| Publicado no: | BMC Musculoskelet Disord |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4301830/ https://ncbi.nlm.nih.gov/pubmed/25510649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-15-431 |
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