Pharmacological targeting of GSK3β confers protection against podocytopathy and proteinuria by desensitizing mitochondrial permeability transition

BACKGROUND AND PURPOSE: Mitochondrial dysfunction, triggered by mitochondria permeability transition (MPT), has been centrally implicated in the pathogenesis of podocytopathy and involves a multitude of cell signalling mechanisms, among which, glycogen synthase kinase (GSK) 3β has emerged as the int...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Wang, Zhen, Bao, Hui, Ge, Yan, Zhuang, Shougang, Peng, Ai, Gong, Rujun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301697/
https://ncbi.nlm.nih.gov/pubmed/25262943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12952
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