Tubulin acetylation promoting potency and absorption efficacy of deacetylase inhibitors

BACKGROUND AND PURPOSE: Histone deacetylase 6 (HDAC6) and silent information regulator 2 (SIRT2) control the dynamics of the microtubule network via their deacetylase activities. Tubulin polymerization promoting protein (TPPP/p25) enhances microtubule acetylation by its direct binding to HDAC6. Our...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Br J Pharmacol
Asıl Yazarlar: Mangas-Sanjuan, V, Oláh, J, Gonzalez-Alvarez, I, Lehotzky, A, Tőkési, N, Bermejo, M, Ovádi, J
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Research Papers
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301692/
https://ncbi.nlm.nih.gov/pubmed/25257800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12946
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