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Modulation Of Microtubule Acetylation By The Interplay Of TPPP/p25, SIRT2 And New Anticancer Agents With Anti-SIRT2 Potency

The microtubule network exerts multifarious functions controlled by its decoration with various proteins and post-translational modifications. The disordered microtubule associated Tubulin Polymerization Promoting Protein (TPPP/p25) and the NAD(+)-dependent tubulin deacetylase sirtuin-2 (SIRT2) play...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Szabó, Adél, Oláh, Judit, Szunyogh, Sándor, Lehotzky, Attila, Szénási, Tibor, Csaplár, Marianna, Schiedel, Matthias, Lőw, Péter, Jung, Manfred, Ovádi, Judit
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5719079/
https://ncbi.nlm.nih.gov/pubmed/29213065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17381-3
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