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Small Molecule Substrate Phosphorylation Site Inhibitors of Protein Kinases: Approaches and Challenges

[Image: see text] Protein kinases are important mediators of cellular communication and attractive drug targets for many diseases. Although success has been achieved with developing ATP-competitive kinase inhibitors, the disadvantages of ATP-competitive inhibitors have led to increased interest in t...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Breen, Meghan E., Soellner, Matthew B.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2014
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4301090/
https://ncbi.nlm.nih.gov/pubmed/25494294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5008376
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