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p38MAPK and MK2 Pathways Are Important for the Differentiation-Dependent Human Papillomavirus Life Cycle

Amplification of human papillomaviruses (HPV) is dependent on the ATM DNA damage pathway. In cells with impaired p53 activity, DNA damage repair requires the activation of p38MAPK along with MAPKAP kinase 2 (MK2). In HPV-positive cells, phosphorylation of p38 and MK2 proteins was induced along with...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Satsuka, Ayano, Mehta, Kavi, Laimins, Laimonis
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300735/
https://ncbi.nlm.nih.gov/pubmed/25410865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02712-14
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