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p38MAPK and MK2 Pathways Are Important for the Differentiation-Dependent Human Papillomavirus Life Cycle

Amplification of human papillomaviruses (HPV) is dependent on the ATM DNA damage pathway. In cells with impaired p53 activity, DNA damage repair requires the activation of p38MAPK along with MAPKAP kinase 2 (MK2). In HPV-positive cells, phosphorylation of p38 and MK2 proteins was induced along with...

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Vydáno v:J Virol
Hlavní autoři: Satsuka, Ayano, Mehta, Kavi, Laimins, Laimonis
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300735/
https://ncbi.nlm.nih.gov/pubmed/25410865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02712-14
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