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The E7 Open Reading Frame Acts in cis and in trans To Mediate Differentiation-Dependent Activities in the Human Papillomavirus Type 16 Life Cycle

Human papillomaviruses (HPVs) are the causative agents of several important genital and other mucosal cancers. The HPV16 E7 gene encodes a viral oncogene that is necessary for the continued growth of cancer cells, but its role in the normal, differentiation-dependent life cycle of the virus is not f...

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Autors principals: Bodily, Jason M., Mehta, Kavi P. M., Cruz, Linda, Meyers, Craig, Laimins, Laimonis A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165838/
https://ncbi.nlm.nih.gov/pubmed/21697473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00664-11
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