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Human Papillomaviruses Activate and Recruit SMC1 Cohesin Proteins for the Differentiation-Dependent Life Cycle through Association with CTCF Insulators

Human papillomaviruses infect stratified epithelia and link their productive life cycle to the differentiation state of the host cell. Productive viral replication or amplification is restricted to highly differentiated suprabasal cells and is dependent on the activation of the ATM DNA damage pathwa...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Mehta, Kavi, Gunasekharan, Vignesh, Satsuka, Ayano, Laimins, Laimonis A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4395367/
https://ncbi.nlm.nih.gov/pubmed/25875106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004763
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