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Human Papillomaviruses Modulate MicroRNA 145 Expression To Directly Control Genome Amplification

Human papillomaviruses (HPVs) modulate expression of host microRNAs. Our deep-sequencing analysis of organotypic raft cultures identified microRNA 145 (miR-145) as a differentiation-dependent microRNA that has functionally active target sequences in the HPV-31 E1 and E2 open reading frames. Overexpr...

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Bibliografiske detaljer
Main Authors: Gunasekharan, Vignesh, Laimins, Laimonis A.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3648148/
https://ncbi.nlm.nih.gov/pubmed/23468503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00153-13
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