Bisphosphonates and statins inhibit expression and secretion of MIP-1α via suppression of Ras/MEK/ERK/AML-1A and Ras/PI3K/Akt/AML-1A pathways

Osteolytic bone disease in multiple myeloma (MM) is associated with upregulated osteoclast activity. Macrophage inflammatory protein-1α (MIP-1α) is crucially involved in the development of osteolytic bone lesions in MM. We previously reported that minodronate inhibited lipopolysaccharide-induced MIP...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Cancer Res
Egile Nagusiak: Tsubaki, Masanobu, Takeda, Tomoya, Sakamoto, Kotaro, Shimaoka, Hirotaka, Fujita, Arisa, Itoh, Tatsuki, Imano, Motohiro, Mashimo, Kenji, Fujiwara, Daiichiro, Sakaguchi, Katsuhiko, Satou, Takao, Nishida, Shozo
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: e-Century Publishing Corporation 2014
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300689/
https://ncbi.nlm.nih.gov/pubmed/25628928
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak