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Engineering synthetic antibody binders for allosteric inhibition of prolactin receptor signaling
BACKGROUND: Many receptors function by binding to multiple ligands, each eliciting a distinct biological output. The extracellular domain of the human prolactin receptor (hPRL-R) uses an identical epitope to bind to both prolactin (hPRL) and growth hormone (hGH), yet little is known about how each h...
में बचाया:
| में प्रकाशित: | Cell Commun Signal |
|---|---|
| मुख्य लेखकों: | , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
BioMed Central
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300558/ https://ncbi.nlm.nih.gov/pubmed/25589173 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-014-0080-8 |
| टैग : |
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