Structure of a mammalian ryanodine receptor

Ryanodine receptors (RyRs) mediate rapid release of calcium (Ca(2+)) from intracellular stores into the cytosol, which is essential for numerous cellular functions including excitation-contraction coupling in muscle. Lack of sufficient structural detail has impeded understanding of RyR gating and re...

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Foilsithe in:Nature
Main Authors: Zalk, Ran, Clarke, Oliver B., des Georges, Amédée, Grassucci, Robert A., Reiken, Steven, Mancia, Filippo, Hendrickson, Wayne A., Frank, Joachim, Marks, Andrew R.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4300236/
https://ncbi.nlm.nih.gov/pubmed/25470061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13950
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