Caricamento...
Structural basis for gating and activation of RyR1
The type-1 ryanodine receptor (RyR1) is an intracellular calcium (Ca(2+)) release channel required for skeletal muscle contraction. Here we present cryo-EM reconstructions of RyR1 in multiple functional states revealing the structural basis of channel gating and ligand-dependent activation. Binding...
Salvato in:
| Pubblicato in: | Cell |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5142848/ https://ncbi.nlm.nih.gov/pubmed/27662087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.075 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|