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Structure of a mammalian ryanodine receptor
Ryanodine receptors (RyRs) mediate rapid release of calcium (Ca(2+)) from intracellular stores into the cytosol, which is essential for numerous cellular functions including excitation-contraction coupling in muscle. Lack of sufficient structural detail has impeded understanding of RyR gating and re...
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| Pubblicato in: | Nature |
|---|---|
| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4300236/ https://ncbi.nlm.nih.gov/pubmed/25470061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13950 |
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