Neuropathological and biochemical assessments of an Alzheimer’s disease patient treated with the γ-secretase inhibitor semagacestat

Amyloid deposition has been implicated as the key determinant of Alzheimer’s disease (AD) pathogenesis. Interventions to antagonize amyloid accumulation and mitigate dementia are now under active investigation. We conducted a combined clinical, biochemical and neuropathological assessment of a parti...

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Bibliografske podrobnosti
izdano v:Am J Neurodegener Dis
Main Authors: Roher, Alex E, Maarouf, Chera L, Kokjohn, Tyler A, Whiteside, Charisse M, Kalback, Walter M, Serrano, Geidy, Belden, Christine, Liebsack, Carolyn, Jacobson, Sandra A, Sabbagh, Marwan N, Beach, Thomas G
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2014
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299724/
https://ncbi.nlm.nih.gov/pubmed/25628963
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