Neuropathological and biochemical assessments of an Alzheimer’s disease patient treated with the γ-secretase inhibitor semagacestat

Amyloid deposition has been implicated as the key determinant of Alzheimer’s disease (AD) pathogenesis. Interventions to antagonize amyloid accumulation and mitigate dementia are now under active investigation. We conducted a combined clinical, biochemical and neuropathological assessment of a parti...

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Библиографические подробности
Опубликовано в: :Am J Neurodegener Dis
Главные авторы: Roher, Alex E, Maarouf, Chera L, Kokjohn, Tyler A, Whiteside, Charisse M, Kalback, Walter M, Serrano, Geidy, Belden, Christine, Liebsack, Carolyn, Jacobson, Sandra A, Sabbagh, Marwan N, Beach, Thomas G
Формат: Artigo
Язык:Inglês
Опубликовано: e-Century Publishing Corporation 2014
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Original Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299724/
https://ncbi.nlm.nih.gov/pubmed/25628963
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