Neuropathological and biochemical assessments of an Alzheimer’s disease patient treated with the γ-secretase inhibitor semagacestat

Amyloid deposition has been implicated as the key determinant of Alzheimer’s disease (AD) pathogenesis. Interventions to antagonize amyloid accumulation and mitigate dementia are now under active investigation. We conducted a combined clinical, biochemical and neuropathological assessment of a parti...

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Detalhes bibliográficos
Publicado no:Am J Neurodegener Dis
Main Authors: Roher, Alex E, Maarouf, Chera L, Kokjohn, Tyler A, Whiteside, Charisse M, Kalback, Walter M, Serrano, Geidy, Belden, Christine, Liebsack, Carolyn, Jacobson, Sandra A, Sabbagh, Marwan N, Beach, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2014
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299724/
https://ncbi.nlm.nih.gov/pubmed/25628963
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