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Neuropathological and biochemical assessments of an Alzheimer’s disease patient treated with the γ-secretase inhibitor semagacestat

Amyloid deposition has been implicated as the key determinant of Alzheimer’s disease (AD) pathogenesis. Interventions to antagonize amyloid accumulation and mitigate dementia are now under active investigation. We conducted a combined clinical, biochemical and neuropathological assessment of a parti...

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Detalles Bibliográficos
Publicado en:Am J Neurodegener Dis
Main Authors: Roher, Alex E, Maarouf, Chera L, Kokjohn, Tyler A, Whiteside, Charisse M, Kalback, Walter M, Serrano, Geidy, Belden, Christine, Liebsack, Carolyn, Jacobson, Sandra A, Sabbagh, Marwan N, Beach, Thomas G
Formato: Artigo
Idioma:Inglês
Publicado: e-Century Publishing Corporation 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299724/
https://ncbi.nlm.nih.gov/pubmed/25628963
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