Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy

The characteristic neuropathological changes associated with Alzheimer’s disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...

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Detalhes bibliográficos
Main Authors: Roher, Alex E., Cribbs, David H., Kim, Ronald C., Maarouf, Chera L., Whiteside, Charisse M., Kokjohn, Tyler A., Daugs, Ian D., Head, Elizabeth, Liebsack, Carolyn, Serrano, Geidy, Belden, Christine, Sabbagh, Marwan N., Beach, Thomas G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605408/
https://ncbi.nlm.nih.gov/pubmed/23555764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059735
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