Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy

The characteristic neuropathological changes associated with Alzheimer’s disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...

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Bibliografiske detaljer
Main Authors: Roher, Alex E., Cribbs, David H., Kim, Ronald C., Maarouf, Chera L., Whiteside, Charisse M., Kokjohn, Tyler A., Daugs, Ian D., Head, Elizabeth, Liebsack, Carolyn, Serrano, Geidy, Belden, Christine, Sabbagh, Marwan N., Beach, Thomas G.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605408/
https://ncbi.nlm.nih.gov/pubmed/23555764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059735
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