Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy

The characteristic neuropathological changes associated with Alzheimer’s disease (AD) and other lines of evidence support the amyloid cascade hypothesis. Viewing amyloid deposits as the prime instigator of dementia has now led to clinical trials of multiple strategies to remove or prevent their form...

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Autori principali: Roher, Alex E., Cribbs, David H., Kim, Ronald C., Maarouf, Chera L., Whiteside, Charisse M., Kokjohn, Tyler A., Daugs, Ian D., Head, Elizabeth, Liebsack, Carolyn, Serrano, Geidy, Belden, Christine, Sabbagh, Marwan N., Beach, Thomas G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2013
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605408/
https://ncbi.nlm.nih.gov/pubmed/23555764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0059735
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