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IL-33–Dependent Type 2 Inflammation during Rhinovirus-induced Asthma Exacerbations In Vivo

Rationale: Rhinoviruses are the major cause of asthma exacerbations; however, its underlying mechanisms are poorly understood. We hypothesized that the epithelial cell–derived cytokine IL-33 plays a central role in exacerbation pathogenesis through augmentation of type 2 inflammation. Objectives: To...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Crit Care Med
Asıl Yazarlar: Jackson, David J., Makrinioti, Heidi, Rana, Batika M. J., Shamji, Betty W. H., Trujillo-Torralbo, Maria-Belen, Footitt, Joseph, Jerico del-Rosario, Telcian, Aurica G., Nikonova, Alexandra, Zhu, Jie, Aniscenko, Julia, Gogsadze, Leila, Bakhsoliani, Eteri, Traub, Stephanie, Dhariwal, Jaideep, Porter, James, Hunt, Duncan, Hunt, Toby, Hunt, Trevor, Stanciu, Luminita A., Khaitov, Musa, Bartlett, Nathan W., Edwards, Michael R., Kon, Onn Min, Mallia, Patrick, Papadopoulos, Nikolaos G., Akdis, Cezmi A., Westwick, John, Edwards, Matthew J., Cousins, David J., Walton, Ross P., Johnston, Sebastian L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299647/
https://ncbi.nlm.nih.gov/pubmed/25350863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201406-1039OC
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