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A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

BACKGROUND: Rhinovirus infection is a major cause of asthma exacerbations. OBJECTIVES: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. METHODS: We used nasosorption on days 0, 2–5 and 7 and bronchosorption at baseline and day...

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Détails bibliographiques
Publié dans:EBioMedicine
Auteurs principaux: Hansel, Trevor T., Tunstall, Tanushree, Trujillo-Torralbo, Maria-Belen, Shamji, Betty, del-Rosario, Ajerico, Dhariwal, Jaideep, Kirk, Paul D.W., Stumpf, Michael P.H., Koopmann, Jens, Telcian, Aurica, Aniscenko, Julia, Gogsadze, Leila, Bakhsoliani, Eteri, Stanciu, Luminita, Bartlett, Nathan, Edwards, Michael, Walton, Ross, Mallia, Patrick, Hunt, Toby M., Hunt, Trevor L., Hunt, Duncan G., Westwick, John, Edwards, Matthew, Kon, Onn Min, Jackson, David J., Johnston, Sebastian L.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440599/
https://ncbi.nlm.nih.gov/pubmed/28373098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.033
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