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A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

BACKGROUND: Rhinovirus infection is a major cause of asthma exacerbations. OBJECTIVES: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. METHODS: We used nasosorption on days 0, 2–5 and 7 and bronchosorption at baseline and day...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Hansel, Trevor T., Tunstall, Tanushree, Trujillo-Torralbo, Maria-Belen, Shamji, Betty, del-Rosario, Ajerico, Dhariwal, Jaideep, Kirk, Paul D.W., Stumpf, Michael P.H., Koopmann, Jens, Telcian, Aurica, Aniscenko, Julia, Gogsadze, Leila, Bakhsoliani, Eteri, Stanciu, Luminita, Bartlett, Nathan, Edwards, Michael, Walton, Ross, Mallia, Patrick, Hunt, Toby M., Hunt, Trevor L., Hunt, Duncan G., Westwick, John, Edwards, Matthew, Kon, Onn Min, Jackson, David J., Johnston, Sebastian L.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440599/
https://ncbi.nlm.nih.gov/pubmed/28373098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.033
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