A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

BACKGROUND: Rhinovirus infection is a major cause of asthma exacerbations. OBJECTIVES: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. METHODS: We used nasosorption on days 0, 2–5 and 7 and bronchosorption at baseline and day...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Hansel, Trevor T., Tunstall, Tanushree, Trujillo-Torralbo, Maria-Belen, Shamji, Betty, del-Rosario, Ajerico, Dhariwal, Jaideep, Kirk, Paul D.W., Stumpf, Michael P.H., Koopmann, Jens, Telcian, Aurica, Aniscenko, Julia, Gogsadze, Leila, Bakhsoliani, Eteri, Stanciu, Luminita, Bartlett, Nathan, Edwards, Michael, Walton, Ross, Mallia, Patrick, Hunt, Toby M., Hunt, Trevor L., Hunt, Duncan G., Westwick, John, Edwards, Matthew, Kon, Onn Min, Jackson, David J., Johnston, Sebastian L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440599/
https://ncbi.nlm.nih.gov/pubmed/28373098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.033
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