A Comprehensive Evaluation of Nasal and Bronchial Cytokines and Chemokines Following Experimental Rhinovirus Infection in Allergic Asthma: Increased Interferons (IFN-γ and IFN-λ) and Type 2 Inflammation (IL-5 and IL-13)

BACKGROUND: Rhinovirus infection is a major cause of asthma exacerbations. OBJECTIVES: We studied nasal and bronchial mucosal inflammatory responses during experimental rhinovirus-induced asthma exacerbations. METHODS: We used nasosorption on days 0, 2–5 and 7 and bronchosorption at baseline and day...

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Publicado en:EBioMedicine
Autores principales: Hansel, Trevor T., Tunstall, Tanushree, Trujillo-Torralbo, Maria-Belen, Shamji, Betty, del-Rosario, Ajerico, Dhariwal, Jaideep, Kirk, Paul D.W., Stumpf, Michael P.H., Koopmann, Jens, Telcian, Aurica, Aniscenko, Julia, Gogsadze, Leila, Bakhsoliani, Eteri, Stanciu, Luminita, Bartlett, Nathan, Edwards, Michael, Walton, Ross, Mallia, Patrick, Hunt, Toby M., Hunt, Trevor L., Hunt, Duncan G., Westwick, John, Edwards, Matthew, Kon, Onn Min, Jackson, David J., Johnston, Sebastian L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5440599/
https://ncbi.nlm.nih.gov/pubmed/28373098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.033
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