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A computational study of the Warburg effect identifies metabolic targets inhibiting cancer migration

Over the last decade, the field of cancer metabolism has mainly focused on studying the role of tumorigenic metabolic rewiring in supporting cancer proliferation. Here, we perform the first genome-scale computational study of the metabolic underpinnings of cancer migration. We build genome-scale met...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Yizhak, Keren, Le Dévédec, Sylvia E, Rogkoti, Vasiliki Maria, Baenke, Franziska, de Boer, Vincent C, Frezza, Christian, Schulze, Almut, van de Water, Bob, Ruppin, Eytan
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299514/
https://ncbi.nlm.nih.gov/pubmed/25086087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20134993
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