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Phenotype-based cell-specific metabolic modeling reveals metabolic liabilities of cancer
Utilizing molecular data to derive functional physiological models tailored for specific cancer cells can facilitate the use of individually tailored therapies. To this end we present an approach termed PRIME for generating cell-specific genome-scale metabolic models (GSMMs) based on molecular and p...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4238051/ https://ncbi.nlm.nih.gov/pubmed/25415239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03641 |
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