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New Insights into Wnt–Lrp5/6–β-Catenin Signaling in Mechanotransduction

Mechanical loading is essential to maintain normal bone metabolism and the balance between bone formation and resorption. The cellular mechanisms that control mechanotransduction are not fully defined, but several key pathways have been identified. We discuss the roles of several components of the W...

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Detalhes bibliográficos
Publicado no:Front Endocrinol (Lausanne)
Main Authors: Kang, Kyung Shin, Robling, Alexander G.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299511/
https://ncbi.nlm.nih.gov/pubmed/25653639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2014.00246
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