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HPMA Copolymer CXCR4 Antagonist Conjugates Substantially Inhibited the Migration of Prostate Cancer Cells

[Image: see text] A N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer–CXCR4 antagonist (BKT140) conjugate (P-BKT140) was developed and its biological activities were tested. Both free BKT140 and monomer MA-GGPLGLAG-BKT140 (MA is methacryloyl) were prepared by solid phase synthesis. P-BKT140 was pre...

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Publicado en:ACS Macro Lett
Autores principales: Peng, Zheng-Hong, Kopeček, Jindřich
Formato: Artigo
Lenguaje:Inglês
Publicado: American Chemical Society 2014
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4299399/
https://ncbi.nlm.nih.gov/pubmed/25621190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mz5006537
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