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Selective inhibitory effect of HPMA copolymer-cyclopamine conjugate on prostate cancer stem cells
Improved treatments for prostate cancer are in great need to overcome lethal recurrence and metastasis. Targeting the tumorigenic cancer stem cells (CSCs) with self-renewal and differentiation capacity appears to be a promising strategy. Blockade of the hedgehog (Hh) signaling pathway, an important...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3242878/ https://ncbi.nlm.nih.gov/pubmed/22138033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.11.029 |
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