Binding of Thienamycin and Clavulanic Acid to the Penicillin-Binding Proteins of Escherichia coli K-12

Thienamycin and clavulanic acid are new β-lactam derivatives with structures markedly different from those of penicillins or cephalosporins. Both derivatives had the same general mode of action as typical β-lactam antibiotics since they bound to precisely the same proteins as [(14)C]benzylpenicillin...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Spratt, Brian G., Jobanputra, Vinay, Zimmermann, Willy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1977
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/334066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.3.406
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