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Binding of Thienamycin and Clavulanic Acid to the Penicillin-Binding Proteins of Escherichia coli K-12

Thienamycin and clavulanic acid are new β-lactam derivatives with structures markedly different from those of penicillins or cephalosporins. Both derivatives had the same general mode of action as typical β-lactam antibiotics since they bound to precisely the same proteins as [(14)C]benzylpenicillin...

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Main Authors: Spratt, Brian G., Jobanputra, Vinay, Zimmermann, Willy
格式: Artigo
語言:Inglês
出版: 1977
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC429926/
https://ncbi.nlm.nih.gov/pubmed/334066
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