Comparison of the Actions of 5-Fluorouracil and Ftorafur in Escherichia coli

The actions of 5-fluorouracil (FU) and Ftorafur (NCS 148958) were compared in Escherichia coli B3 to determine if Ftorafur can act in ways other than through the production of FU. Very high concentrations of Ftorafur relative to FU were necessary to achieve a comparable inhibition of cell growth. In...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Saunders, Priscilla P., Chao, Lian-Yu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1977
Assuntos:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/324392/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.3.451
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