Comparison of the Actions of 5-Fluorouracil and Ftorafur in Escherichia coli

The actions of 5-fluorouracil (FU) and Ftorafur (NCS 148958) were compared in Escherichia coli B3 to determine if Ftorafur can act in ways other than through the production of FU. Very high concentrations of Ftorafur relative to FU were necessary to achieve a comparable inhibition of cell growth. In...

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Pubblicato in:	Antimicrob Agents Chemother
Autori principali:	Saunders, Priscilla P., Chao, Lian-Yu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1977
Soggetti:	Biosynthesis; Chemistry; Mechanisms of Action and Resistance
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC352006/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/324392/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.11.3.451
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