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Biotransformation of Sisomicin to Gentamicin C(2b)

Sisomicin was transformed to gentamicin C(2b) by Micromonospora rhodorangea NRRL 5326. The mechanisms involved in the biotransformation are the 6′-N-methylation and the (4′-5′)-reduction. The progression of the methylation was followed by the isotope technique, but the reduction reaction was not mon...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Lee, B. K., Bailey, J. V., Condon, R. G., Marquez, J. A., Wagman, G. H., Weinstein, M. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1977
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429914/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/907326/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.12.3.335
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