(1)H-NMR and Hyperpolarized (13)C-NMR Assays of Pyruvate-Lactate Exhange: a comparative study

Pyruvate-lactate exchange is mediated by the enzyme lactate dehydrogenase (LDH) and is central to the altered energy metabolism in cancer cells. Measurement of exchange kinetics using hyperpolarized (13)C NMR has provided a biomarker of response to novel therapeutics. In this study we investigated a...

Full description

Saved in:
Bibliographic Details
Published in:NMR Biomed
Main Authors: Hill, Deborah K., Jamin, Yann, Orton, Matthew R., Tardif, Nicolas, Parkes, Harold G., Robinson, Simon P., Leach, Martin O., Chung, Yuen-Li, Eykyn, Thomas R.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4298370/
https://ncbi.nlm.nih.gov/pubmed/23712817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2957
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items