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(1)H-NMR and Hyperpolarized (13)C-NMR Assays of Pyruvate-Lactate Exhange: a comparative study
Pyruvate-lactate exchange is mediated by the enzyme lactate dehydrogenase (LDH) and is central to the altered energy metabolism in cancer cells. Measurement of exchange kinetics using hyperpolarized (13)C NMR has provided a biomarker of response to novel therapeutics. In this study we investigated a...
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| Publicado no: | NMR Biomed |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4298370/ https://ncbi.nlm.nih.gov/pubmed/23712817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/nbm.2957 |
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