Model Free Approach to Kinetic Analysis of Real-Time Hyperpolarized (13)C Magnetic Resonance Spectroscopy Data

Real-time detection of the rates of metabolic flux, or exchange rates of endogenous enzymatic reactions, is now feasible in biological systems using Dynamic Nuclear Polarization Magnetic Resonance. Derivation of reaction rate kinetics from this technique typically requires multi-compartmental modeli...

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Detalhes bibliográficos
Main Authors: Hill, Deborah K., Orton, Matthew R., Mariotti, Erika, Boult, Jessica K. R., Panek, Rafal, Jafar, Maysam, Parkes, Harold G., Jamin, Yann, Miniotis, Maria Falck, Al-Saffar, Nada M. S., Beloueche-Babari, Mounia, Robinson, Simon P., Leach, Martin O., Chung, Yuen-Li, Eykyn, Thomas R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762840/
https://ncbi.nlm.nih.gov/pubmed/24023724
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0071996
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