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Metabolic assessment of the action of targeted cancer therapeutics using magnetic resonance spectroscopy

Developing rational targeted cancer drugs requires the implementation of pharmacodynamic (PD), preferably non-invasive, biomarkers to aid response assessment and patient follow-up. Magnetic resonance spectroscopy (MRS) allows the non-invasive study of tumour metabolism. We describe the MRS-detectabl...

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Detalhes bibliográficos
Main Authors: Beloueche-Babari, M, Chung, Y-L, Al-Saffar, N M S, Falck-Miniotis, M, Leach, M O
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2813738/
https://ncbi.nlm.nih.gov/pubmed/19935796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605457
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